Collectors are essential reagents in the froth flotation process, used to separate valuable minerals from waste materials in the mining industry. They selectively adsorb onto target mineral particles, making them hydrophobic and enabling them to attach to air bubbles and float to the surface. Ionizing collectors, such as xanthates, dithiophosphates, and mercaptans, and non-ionizing collectors, like fatty acids, amines, and petroleum sulfonates, are used for different mineral types. The choice of collector depends on factors such as mineral type, pH, impurities, and desired recovery. Proper handling and storage are crucial for effectiveness and safety. Green collectors based on natural products are being developed to reduce environmental impact while maintaining performance.